Source: UN
President Donald J. Trump on Sept. 23rd pledged that the United States would lead a global effort to strengthen safeguards against biological weapons, telling the United Nations General Assembly that his administration would spearhead the creation of an artificial intelligence–based verification system to enforce the Biological Weapons Convention.
“My administration will lead an international effort to enforce the biological weapons convention,” Mr. Trump said. “We will do so by pioneering an AI verification system that everyone can trust.” His remarks reflected Washington’s ambition to harness cutting-edge technologies to confront the rising risk of engineered pathogens.
An American Tradition of Leadership
The United States has long sought to place itself at the forefront of biological arms control. In 1969, it formally renounced any offensive biological weapons program; in 1975, it helped bring the Biological Weapons Convention into force. Today, nearly 190 nations are parties to the treaty, and the U.S. has consistently pressed to adapt it to new scientific and technological challenges.
In August, this year, during the Sixth Session of the Working Group on Strengthening the Convention in Geneva, the U.S. again assumed a prominent role. American negotiators pushed for stronger verification, greater transparency, and deeper cooperation to confront emerging biotechnological threats. They backed legally binding compliance provisions, capacity-building initiatives, and expanded confidence-building measures (CBMs), all aimed at updating the treaty for contemporary biological risks. That leadership not only generated momentum toward consensus but also produced tangible steps to reinforce global security and public health amid rapid advances in synthetic biology and AI. Looking ahead, Mr. Trump’s AI initiative is expected to be a centerpiece of debate at the 2026 BWC Review Conference, where states parties will weigh its potential role in shaping the future of biological arms control.
AI Verification as a Safeguard
The risk landscape at the intersection of AI and synthetic biology is changing rapidly. Tools originally developed for protein engineering or drug discovery are increasingly able to model novel toxins or design pathogens, lowering barriers to misuse. With the aid of large language models, even individuals with little biological training could, in theory, create harmful agents or evade conventional biosecurity measures. Such possibilities highlight the vulnerabilities that legitimate research faces in monitoring immune evasion, gene editing, and transmissibility.
Against this backdrop, the system outlined by Mr. Trump represents a shift from traditional state-centered inspections toward a networked, data-driven model. By leveraging artificial intelligence to analyze research data, genetic sequences, and biotechnology transactions, the platform is designed to detect suspicious activity that might indicate the development or stockpiling of biological weapons. In practice, it would operate as a cloud-based network, integrating existing biosurveillance databases and research registries, and using machine learning to flag anomalies in real time.
The U.S. Defense Threat Reduction Agency’s Biosurveillance Ecosystem (BSVE) offers a preview of how such a system could function globally. For example, when an unusual spike in respiratory illness appears in a metropolitan area, BSVE enables analysts to quickly identify outbreak patterns, assess severity, and coordinate responses with local health authorities. It does so by ingesting diverse data streams—from social media posts and news reports to diagnostic results and historical outbreak records—and applying machine learning and natural language processing to detect anomalies. Those insights are then visualized on an analyst dashboard, providing an opportunity for early intervention before localized outbreaks spiral into full epidemics.
Lai Ching-te(R) greeting the crowd with a crossed finger gesture after delivering his speech on Taiwan’s National Day, October 10, 2025.
When President Lai Ching-te unveiled Taiwan’s T-Dome air and missile defense system on National Day, October 10, 2025, the message to Beijing was unmistakable: Taiwan is done waiting to see what comes next.
Taiwan’s T-Dome, the island’s most up-to-date effort to build credible deterrence against China, is a sophisticated, multi-layered air defense network designed to counter diverse aerial threats, from drones to ballistic missiles, by integrating advanced radar systems, interceptor missiles like the domestically developed Sky Bow III and U.S.-supplied Patriot batteries, as well as short-range Stinger missiles. Its AI-driven ‘sensor-to-shooter’ architecture is particularly noteworthy for its capacity to fuse data from radar arrays and sensors to coordinate rapid, precise interception while utilizing mobile launchers and hardened command centers to ensure resilience during sustained attacks. Prioritizing overlapping protection of critical infrastructure and command nodes in strategic areas such as Taipei, Taichung, and Kaohsiung, the Lai administration has positioned the T-Dome as the centerpiece of its defense modernization agenda, anchored in resilience and indigenous innovation. To maintain operational capacity amid growing Chinese military pressure, Taipei now aims to strategically invest in T-Dome. By 2026, Taiwan plans to push defense spending past 3 percent of GDP, targeting 5 percent by 2030.
The urgency in Taiwan demonstrated by the T-Dome is clear. Beijing now asserts sovereignty over Taiwan and continues to refuse to rule out the use of force to achieve unification. Throughout 2025, the People’s Liberation Army (PLA) significantly expanded its operational reach around Taiwan. The Chinese air force deployed advanced fighter jets such as the J-10, J-16, and J-20, which can now reach Taiwan from bases deep within China without refueling. Taiwan’s Ministry of National Defense reported that PLA aircraft entered Taiwan’s air defense identification zone (ADIZ) over 245 times per month in 2025, a steep increase from fewer than 10 times per month five years earlier. Alongside its increased intrusion into the ADIZ, it is estimated that PLA aircraft are crossing the Taiwan Strait median line roughly 120 times monthly, marking unprecedented levels of military pressure on Taiwan.
This heightened activity reached a new peak in early April 2025, when the PLA conducted its largest exercise to date, ‘Strait Thunder-2025A’ on April 1–2. This operation, the biggest since 2024’s ‘Joint Sword 2024B,’ further escalated tensions across the strait while politically propagandizing the Lai administration as ‘verminous insects’ conspiring for ‘Taiwan independence.’ The exercise simulated precision strikes against Taiwan’s energy infrastructure and ports, involving 76 aircraft sorties (37 crossing the Taiwan Strait median line), over 15 naval vessels including the Shandong carrier group, and coast guard ships extending outside the First Island Chain. The increasing instances of escalatory activities are part of the PLA’s broader “gray zone” campaign, designed to exhaust Taiwan’s defenses without triggering open warfare. Taiwan’s Defense Ministry analyzes that China is honing such capabilities for a possible military operation as early as 2027, aligned with major PLA modernization milestones.
The U.S. continuously seeks peace and stability in the Taiwan Strait
With respect to Lai’s announcement of the T-Dome, the U.S. Department of State expressed continuous American support for Taiwan’s efforts to strengthen its defensive and deterrence capabilities. Ensuring peace and stability in the Taiwan Strait remains the United States’ highest priority and serves as the fundamental purpose of the Taiwan Relations Act (TRA). Enacted by the U.S. Congress in 1979, following President Jimmy Carter’s formal recognition of the People’s Republic of China, the TRA provides the essential legal framework that guarantees Taiwan’s ability to maintain adequate self-defense capabilities in response to evolving threats. The Act also underpins the continuation of robust U.S. commercial, cultural, and defensive relations with Taiwan. Since its enactment, key developments under the TRA include the establishment of the American Institute in Taiwan, which manages unofficial relations, and congressional mandates ensuring that the United States stays prepared to effectively respond to any threats to Taiwan’s security.